The conjugation of DNA/RNA oligonucleotides with various ligands to enhance their delivery, stability, and specificity for targeted therapeutics has become a cornerstone in the development of next-generation molecular therapies. These ligands can facilitate targeted delivery to specific tissues, cells, or intracellular compartments, thereby improving the therapeutic index of oligonucleotides. Beyond cholesterol, folic acid, and spermine, a wide range of ligands have been explored for these purposes. This Podcast episode gives a detailed overview of the classes and examples of ligands used in oligonucleotide conjugation.
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Targeted Therapeutics, Oligonucleotide Conjugates for Transfection, Nucleic Acid Therapeutics
Luke McLaughlin, Biotech Digital Marketer, Business Developer and Life Science Content Creator
Jul 07, 2024

BioTechRvs Biotechnology Reviews Journal
Biotechnology Reviews mission is to be a knowledge bridge, providing articles covering cutting edge research and developments beyond mere headlines. Providing both the backbone and structural knowledge at all levels of interest to Biotechnology enthusiasts, professionals, investors and scientists.
Our comprehensive journal delves deep into the most relevant research, providing you with valuable insights into emerging trends, cutting-edge innovations, and significant developments that are shaping the biotech industry.
Biotechnology Reviews mission is to be a knowledge bridge, providing articles covering cutting edge research and developments beyond mere headlines. Providing both the backbone and structural knowledge at all levels of interest to Biotechnology enthusiasts, professionals, investors and scientists.
Our comprehensive journal delves deep into the most relevant research, providing you with valuable insights into emerging trends, cutting-edge innovations, and significant developments that are shaping the biotech industry.Listen on
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